It’s a Genetic Condition
The Tuberous Sclerosis Alliance explains that TSC is a genetic condition, meaning it’s in the family bloodlines. The disease can be inherited from just one parent with the condition, or it can “result from a spontaneous genetic mutation,” adds the source.
The source also notes that children have a 50-percent chance of inheriting TSC if one parent has it. However, while it’s considered a genetic condition, “only one-third of TSC cases are known to be inherited,” says the alliance. The other cases are the result of the aforementioned genetic mutation during conception or early development that’s unpredictable.
There Are a Range of Symptoms
As mentioned before, the symptoms can differ on a case-by-case basis due to the location of the tumors. With that being said, there are some relatively mild to quite serious health complications that are associated with TSC.
Healthline.com explains aside from those who have mild symptoms that may not warrant much concern, others can experience developmental delay, autism, intellectual disabilities, seizures, and skin abnormalities. “This disorder can be present at birth, but symptoms may be mild at first, taking years to develop fully,” adds the source.
It Can Be Life-Threatening
To build on the list of symptoms, in some cases, TSC can be more than an inconvenience to a patient, it can be deadly. The Mayo Clinic reports there can be serious complications such as excess fluid in or around the brain due to a blockage of a ventricle in the brain (a condition known clinically as hydrocephalus).
Meanwhile, there can also be heart complications, such as blocked blood flow or irregular rhythm, as well as kidney damage, lung failure, vision problems, and an increased risk of developing cancerous tumors in the kidneys and brain, adds the source.