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Signs and Symptoms of Sickle Cell Anemia


2. Fever

“Crises” or episodes of pain and discomfort that can last for days are the most visible symptom of sickle cell anemia. However, these difficult episodes are hardly the only sign of the illness. A generally less serious symptom is fever, which may be the first sign that trouble, including a crisis, is on the way.

Anyone with sickle cell anemia should keep an electric thermometer nearby so that they can carefully monitor their temperature and take action if a fever starts to emerge. Many patients will find that a fever reaching a certain temperature can mark the starting point of more serious symptoms, such as intense joint pain.

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