Home » Your Health » 12 Skin Pigmentation Disorders

12 Skin Pigmentation Disorders

Special cells in the skin called melanocytes produce melanin.  Melanin gives rise to skin pigmentation, or coloring.  Disorders of melanin can be characterized by increased melanin production causing skin to get darker (hyperpigmentation) or by decreased melanin production causing skin to get lighter (hypopigmentation).  Skin disorders resulting in hypopigmentation may be acquired or congenital (present from birth).  Acquired causes of hypopigmentation are more common than congenital causes of hypopigmentation.  Collectively, the group of diseases is referred to as skin pigmentation disorders.  Twelve skin pigmentation disorders include…

1. Postinflammatory Hyperpigmentation

Postinflammatory hyperpigmentation (PIH) is common and represents darkening of the skin in an area of prior injury or inflammation.  The lesions may be described as irregular, darkly pigmented macules and patches.  The lesions may persist for months to years.  Conditions such as acne, psoriasis, atopic and contact dermatitis, lichen planus, trauma, drugs, and fixed-drug eruptions may lead to postinflammatory hyperpigmentation.  It may also occur after laser therapy for other skin lesions.  Dark skinned individuals are at higher risk for developing the condition.

Treatment of PIH is often difficult and requires prolonged courses of therapy with excellent patient compliance.  Therapeutic agents for PIH include hydroquinone 3-percent or 4-percent (Eldoquin Forte) twice daily, azelaic acid 20-percent cream (Azelex) twice daily, salicylic or glycolic acid peels, retinoids (Retin-A, Tazorac), and laser therapy.  Monotherapy seldom gives acceptable clinical results.  A clinical trial found serial glycolic acid peels in addition to hydroquinone 2-percent/glycolic acid 10-percent combination twice daily and tretinoin 0.05-percent (Retin-A) at bedtime resulted in faster skin lightening without significant adverse effects.

skin leision

Next »

We Recommend

More on ActiveBeat

  • 7 Foods That Are Bad For Your Skin
    Many people take great pride in having smooth, soft skin that almost seems to radiate outwards, inviting others to touch it.
    Your Health
  • Tattoos Pose Significant Health Risk, Study Suggests
    A new study reveals that tattoos can pose significant health risks. In fact, it finds that roughly one in ten people who get a tattoo will have some kind of associated health...
    Your Health
  • Ehlers-Danlos Syndromes: Causes, Signs, Diagnosis, and Treatment
    You likely haven’t given too much thought to your skin, joints, and blood vessels lately—unless you’ve suffered an wound that required stitches or a joint injury that put you...
    Your Health
  • Tanning Bed Usage on the Decline, Report Shows
    A new study suggests that fewer Americans see using a tanning bed as a critical step towards feeling and looking beautiful.
    Your Health
  • 11 Common Skin Rashes in Children
    Rashes in children are a common occurrence. They represent a reaction and consist of a noticeable change in the texture or color of the skin.
    Your Health
  • The 12 Most Common Adult Skin Disorders
    The skin is the largest and one of the most complex organs of the body. Adults may suffer from a variety of skin disorders with tremendous variation in symptoms and severity.
    Your Health
  • 12 Health Benefits of Turmeric
    If you've tried putting turmeric, the burnt orange colored spice ground from a root, then you're seriously missing out.
    Your Health
  • 12 Benefits of Barley Water to Drink Up
    When you hear the words barley water, some people may make a connection to beer. But the main difference is that barley water hasn't gone through a fermentation process, so there's...
    Your Health
  • 15 Signs of B12 Deficiency in Women
    Did you know that a woman’s ability to absorb the vitamin B12 gradually decreases with age?
    Your Health
  • 7 Foods that Aggravate Psoriasis
    If you suffer from reoccurring psoriasis flare-ups—an autoimmune disorder characterized by rapid skin cell growth that triggers scaly, inflamed, red patches of skin to...
    Your Health
  • 6 Bright Tips for Sun Protection During Summer
    Depending where you live in the U.S., you may have waited months for some of that lovely, warm sunshine.
    Your Health
  • 6 Itchy Truths about Psoriasis for Psoriasis Awareness Month
    Psoriasis is described as "one of the most baffling and persistent of skin disorders" by WebMD, but it affects about 2-percent of the U.S.
    Your Health
  • Video: Breaking Barriers for People with Psoriasis
    The theme for World Psoriasis Day 2016 is "Breaking Barriers for People with Psoriasis". The International Federation of Psoriasis Associations (IFPA) created this colourful...
    Your Health
  • 6 Health Remedies to Treat Minor Burns
    There are a number of ways you can accidentally burn yourself at home or at work – whether you spill some boiling water on your hand from a pot or kettle, touch a hot iron, rest...
    Your Health
  • 6 Treatments for Scleroderma
    Scleroderma is a type of skin disease that can result in the skin becoming abnormally hard and tight, sometimes resulting in redness, discomfort, and pain.
    Your Health