Low Testosterone
Low testosterone (sex hormone) production affects more than sex drive, according to research conducted by the National Institutes of Health. Low testosterone stores, which tend to diminish as we age, can lead to erectile dysfunction in men, as well as low energy, diminished libido, weight gain, bone weakness, hair loss, and ultimately, depression in both sexes. However, hormone replacement therapy can help alleviate these symptoms.

Retirement
Retiring from work can be a new and positive chapter in your life if you fill it with hobbies, travel, and spouse bonding. However, many older adults become depressed shortly after retirement, according to a research study co-conducted by the UK-based Institute of Economic Affairs and the Age Endeavour Fellowship. The study found that during retirement roughly 40-percent of individuals become clinically depressed, while 60-percent develop a physical disorder.

Onset of Menopause
Perimenopause (the transition into menopause) is rife with hot flashes, erratic periods, waning sex drive, mood imbalances, and sleep loss. It’s no wonder that this hormone roller coaster leaves women feeling miserable. A 2006, study of mood cycles by Harvard researchers found that 1 in 6 women with no medical history of depression displayed symptoms of depression during perimenopause.

Not Enough “Me” Time
If you are suffocating under the many obligations of work life, social life, family, parenting, and finances, you risk becoming clinically depressed. In fact, a research study from the US Centers for Disease Control and Prevention (CDC) found that current day Americans are more likely to commit suicide than die in vehicle accidents.
The data reported that suicide rates for middle aged men increased by 50 percent while suicide rates for women increased by 60-percent over the past decade and attributed that depression to the overwhelming demands of caring for their children, spouse, and aging parents. (Here are 10 “Me Time” Tips From the Health Care Professionals).