Home » Health Studies in the News » New Drug Offers Hope For Kidney Patients on Dialysis

New Drug Offers Hope For Kidney Patients on Dialysis


New York based, Keryx Biopharmaceuticals Inc., said a late-stage trial of its experimental drug, Zerenex, for kidney disease met the late-stage trial goal of reducing phosphate levels in blood. The positive results boosted Keryx shares up to 49 percent, selling for $4.80 on Monday’s Nasdaq.

Because phosphate levels in blood rise when kidney function declines, which often results in anemia, Zerenex aims to reduce serum phosphorus levels, or hyperphosphatemia, in patients with end-stage renal disease on dialysis.

Zerenex also increases the levels of two proteins in the blood while reducing the need for intravenous iron and erythropoiesis-stimulating agent (ESA), an agent used to encourage the production of red blood cells. Zerenex, like Renvela and PhosLo, is a phosphate binders that attaches to phosphates in the gastrointestinal tract and prevent them from absorbing into the body.

The company expects to file for regulatory approvals of the drug in the United States and Europe in the second quarter of 2013, and if Zerenex, is approved, it will compete with Genzyme Corp’s, Renagel and Renvela.

Ron Bentsur, Keryx CEO, points to the potential health and pharmaco-economic advantages of the company’s new drug. “… Zerenex is the only phosphate binder that has the potential to transcend into another dialysis category, in this case anemia management.”

Source: Reuters

ADVERTISEMENT

More on ActiveBeat
  • Common Causes of Dark Under-Eye Circles
    We've all been there, dragged ourselves out of bed in the morning after a poor night's sleep only to find our reflection mirrors how we feel!
    Health Studies in the News
  • Symptoms of Celiac Disease: Do You Have It?
    Celiac disease, also known as coeliac disease, is an autoimmune disorder that affects around 1 in 100 Americans. The disease is caused by gluten intolerance.
    Health Studies in the News
  • Common Symptoms of Crohn's Disease
    Crohn's disease is a painful inflammatory condition that affects between 400,000 and 600,000 individuals in North America alone.
    Health Studies in the News
  • Health-Related Reasons For Hair Loss in Women
    According to the American Academy of Dermatology, most people lose between 50 and 100 strands of hair every day.
    Health Studies in the News
  • Common Signs, Symptoms and Treatments For Bone Cancer
    Approximately 3,010 adults will be diagnosed with bone cancer this year. More than 1,400 will die from the disease.  There are several types of bone cancer.
    Health Studies in the News
  • Absorb These Important Facts About Folate Deficiency
    Your body needs many vitamins and nutrients to function properly, and some are talked about more than others.
    Health Studies in the News
  • The Incredible Health Benefits of Copper
    For thousands of years, copper has played an important role in human history. For centuries it was a crucial mineral in the production of everything from weapons to tools and...
    Health Studies in the News
  • Fingernails Provide Windows to Our Health
    You use them to scratch an itch, grip shopping items before picking them from the grocery store shelf, and maybe you even bedazzle them in the season’s hottest shade—but did...
    Health Studies in the News
  • The 10 Most Common Blood Tests (And What They're Used For)
    Medical professionals administer a wide variety of blood tests to diagnose for numerous health concerns—from general issues like anemia and electrolyte deficiency to serious...
    Health Studies in the News
  • Is My Body Trying to Tell Me Something?
    While I hesitate to liken the human body to a machine, your car, just like your body, hardly ever just stops working without adequate warning.
    Health Studies in the News
  • 7 Common Causes of Cold Fingers and Toes
    Are you prone to icy digits? If your fingers and toes are constantly and inexplicably cold even when everyone else is warm, you may be dealing with an underlying health issue.
    Health Studies in the News
  • 10 Nutrient Deficiencies that Can Cause Depression
    Not feeling great lately? It’s possible you’ve picked up a cold or some other kind of infection.
    Health Studies in the News
  • Medical Causes for Shortness of Breath
    Shortness of breath, known medically as dyspnea, refers to difficulty breathing and is a common complaint seen by many physicians. Its occurrence can be acute or chronic.
    Health Studies in the News
  • 6 Early Signs of Colorectal Cancer
    Colorectal cancer is one of the most dangerous forms of the deadly disease—in the United States, it's responsible for the second most cancer deaths.
    Health Studies in the News
  • 12 Causes of Congestive Heart Failure
    Heart failure refers to a condition in which the heart cannot pump enough blood to meet the body’s metabolic needs.  It is often referred to as congestive heart failure, or CHF.
    Health Studies in the News