In severe Crohn’s disease sufferers, painful cramping may be common. As the disease progresses, scar tissue can form around the intestines. As the person eats and the intestines shift, the scar tissue can pull. This can cause incredibly painful cramping. The person may feel nauseated and throw up because of the pain. This can make a Crohn’s sufferer lose the desire to eat because they are so violently ill when they do. Bloating and flatulence in relation to Crohn’s disease can also cause cramping.