2. Inflammation of Internal Organs
A person with primary immunodeficiency may also experience pain in the abdominal area. In many cases, this pain is due to swelling or infection of the spleen or liver caused by autoimmune or inflammatory disease.
According to the Immune Disease Foundation, these conditions can cause “temporary or permanent damage that can disrupt one or more of the liver’s important functions.” Such disruptions, the source adds, “may lead to accumulation of fluid in the abdomen (ascites), elevated bilirubin in the blood leading to jaundice, blood clotting abnormalities, etc.”