Bile is a essential bodily fluid, it travels from the liver via the bile ducts to the small intestine to aid in the digestion of fatty vitamins and fats. However, in patients with Primary Biliary Cholangitis (or PBC), the mode of transport for this digestive liquid, the bile ducts, become chronically inflamed and gradually break down, so that bile stays in the liver where it can scar and damage liver cells and lead to fatal liver disfunction and cirrhosis of the liver.
Let’s examine the causes, signs and symptoms, treatment options, and life expectancy for Primary Biliary Cholangitis…
1. Primary Biliary Cholangitis Causes and Risk Factors
Research from the American Liver Foundation notes that females make up 90-percent of the patients diagnosed with Primary Biliary Cholangitis. The age range of typical diagnosis is usually between 35- and 60-years of age.
However, medical professionals are unsure the exact cause of PBC, they suspect it may result from immune system issues. While Primary Biliary Cholangitis is not considered a hereditary condition, doctors do find that this decease is prevalent in families, siblings in particular, where one member has already been diagnosed.